1998 Dec;39(12):581-6. Dogs that eat pet food containing too much vitamin D can develop vitamin D toxicity. Durtnell RE. Alveolar mineralization with septal rupture due to Vitamin D toxicosis in dog lung. Vitamin D poisoning occurs when a dog ingests a toxic dose of vitamin D. There are two forms of vitamin D – plant-derived vitamin D 2 and animal-derived vitamin D 3 (also called cholecalciferol). In animals with vitamin D toxicity watch for vomiting, diarrhea, anorexia, excessive drinking and urination, depression, hemorrhage (bleeding), abnormal heart rhythms, bone pain and limping. Despite 13 days of intensive supportive care, the dog was euthanased due to continued haematemesis and anorexia. Cholecalciferol (Vitamin D) toxicosis can come from a variety of different sources, with the most common being supplements. Signs : usually develop within 12-36 hours: anorexia, vomiting. Oversupplementation with Vitamin D via the diet can also cause toxicosis, and suckling puppies are particularly susceptible if the dam is oversupplemented. Red–violet deposits in alveolar septa are visible in the center of the image. Common sources of Vitamin D 3 include over-the-counter (OTC) or prescription vitamins (typically found in a calcium/Vitamin D 3 combination), psoriasis creams (in the form of calcipotriene), and rodenticides. Necropsy confirmed mineralisation and necrosis of multiple organ systems consistent with vitamin D toxicity. Most research on this vitamin in dogs has focused on the effects of deficiency. Too little vitamin D is also a problem. Hematoxylin and eosin stain.

Vitamin D is an essential nutrient for most animals, including humans and dogs. A common source of vitamin D poisoning is when a dog accidentally ingests rodenticides containing vitamin D. Some examples of these products include Muritan, Mouse-B-Gone, Mouse Killer, Quintox … But why did the FDA draw a parallel between vitamin D toxicosis in dogs and rodenticide poisoning? These were present diffusely throughout the lung and caused the lung grossly to be hard to the touch, hyperinflated and gritty when cut. Other sources of Vitamin D ingestions include: Cholecalciferol rodenticides, which are very potent and can cause toxicity with just a small exposure. Abdominal ultrasonography and echocardiography revealed evidence of diffuse soft tissue mineralisation. Consequences of Vitamin D Deficiency Dogs: Puppies fed vitamin D deficient diets become lethargic, have poor muscle tone, develop bowing of the limbs (i.e. Dry dog foods from at least eight companies may have harmful excess vitamin D. At least six dogs have been sickened with vitamin D toxicosis, although Food and Drug Administration officials have received no reports of deaths, according to Anne Norris, a spokeswoman for the FDA Center for Veterinary Medicine. Canine vitamin D toxicosis. While humans and certain animals are able to synthesize Vitamin D from the sun via their skin, dogs mainly get Vitamin D from their diets.Although dogs need Vitamin D to survive and thrive, too much Vitamin D can be toxic to dogs. Request PDF | Vitamin D toxicosis | Vitamin D compounds are found in a number of different products. PMID: 10649601 [PubMed - indexed for MEDLINE] Publication Types: Case Reports; Comment; Letter; MeSH Terms. Because they both contain vitamin D, and in large enough doses, vitamin D can cause devastating and irreversible harm. rickets), and diffuse osteopenia with pathologic fractures.In adult dogs, clinical signs of calcium deficiency (e.g. Veterinary Care. Diagnosis is based largely on signs of intoxication coupled with a history of ingestion or oversupplementation. Kidneys, bile, and urine from dogs that died of CCF toxicosis were analyzed for 25 monohydroxy vitamin D 3 (25(OH)D 3) and 1,25 dihydroxy vitamin D 3 (1,25(OH) 2 D 3) and compared to known control unexposed dogs. Comment on J Small Anim Pract.

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